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Home > Research & Development
> Patents Patents
Patents, trademarks, trade secrets, technological know-how and other proprietary rights are important to OPK Biotech's business. As of October 31, 2007 the company holds dozens of patents relating to its oxygen therapeutics, including 28 issued U.S. patents covering the manufacture of ultra-pure and room temperature stable hemoglobin solutions and their use as oxygen therapeutics. Key claims in the U.S. patents are not limited by the hemoglobin source (e.g., animal, human or genetically derived).
| U.S. Patent |
Patent Title |
Date Issued |
| 7,267,817 |
Method for Improving Oxygen Transport by Stored Red Blood Cells |
9/11/2007 |
| 7,135,554 |
Method of Forming A Polymerized Hemoglobin Solution from Stabilized Hemoglobin |
11/14/2006 |
| 7,041,799 |
Preserving A Hemoglobin Blood Substitute With A Transparent Overwrap |
5/9/2006 |
| 7,041,800 |
Preserving A Hemoglobin Blood Substitute With A Transparent Overwrap |
5/9/2006 |
| 7,001,715 |
Purification of Red Blood Cells by Separation and Diafiltration |
2/21/2006 |
| 6,986,984 |
Use of Defibrinated Blood for Manufacture of a Hemoglobin-Based Oxygen Carrier |
1/17/2006 |
| 6,811,778 |
Method for Improving Oxygen Transport by Stored Red Blood Cells |
11/2/2004 |
| 6,610,832 |
Preserving A Hemoglobin Blood Substitute With A Transparent Overwrap |
8/26/2003 |
| 6,541,449 |
Increasing Function of Organs Having Reduced Red Blood Cell Flow |
4/1/2003 |
| 6,518,010 |
Use of Defibrinated Blood for Manufacture of a Hemoglobin-Based Oxygen Carrier |
2/11/2003 |
| 6,506,725 |
Ultra Pure Hemoglobin Solutions and Blood Substitutes (as amended) |
1/14/2003 |
| 6,288,027 |
Preserving A Hemoglobin Blood Substitute With A Transparent Overwrap |
9/11/2001 |
| 6,271,351 |
Method for Preserving A Hemoglobin Blood Substitute |
8/7/2001 |
| 6,150,507 |
Method for Producing A Purified Hemoglobin Product |
11/21/2000 |
| 5,955,581 |
Method for Producing A Stable Polymerized Hemoglobin Blood-Substitute |
9/21/1999 |
| 5,952,470 |
Method for Separating Unmodified Hemoglobin From Cross-Linked Hemoglobin |
9/14/1999 |
| 5,905,141 |
Ultra Pure Hemoglobin Solutions and Blood Substitutes (as amended) |
5/18/1999 |
| 5,895,810 |
Stable Polymerized Hemoglobin and Use Thereof |
4/20/1999 |
| 5,854,209 |
Method For Oxygenating Tissue Having Reduced Red Blood Cell Flow |
12/29/1998 |
| 5,840,852 |
Method for Producing Ultrapure Stable Polymerized Hemoglobin Blood-Substitute |
11/24/1998 |
| 5,808,011 |
A Method for Chromatographic Removal of Prions |
9/15/1998 |
| 5,753,616 |
Method for Producing A Stable Polymerized Hemoglobin Blood-Substitute |
5/19/1998 |
| 5,691,453 |
Separation of Polymerized Hemoglobin from Unpolymerized Hemoglobin on Hydroxyaptite Using HPLC |
11/25/1997 |
| 5,691,452 |
Method for Preserving A Hemoglobin Blood Substitute |
11/25/1997 |
| 5,618,919 |
Ultra Pure Hemoglobin Solutions and Blood Substitutes |
4/8/1997 |
| 5,296,465 |
Ultra Pure Hemoglobin Solutions and Blood Substitutes |
3/22/1994 |
| 5,095,765 |
Sample Valve for Sterile Processing |
3/17/1992 |
| 5,084,558 |
Extra Pure Semi-Synthetic Blood Substitute |
1/28/1992 |
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is a Resource Guide for individuals interested in the impact of OPK Biotech's Hemoglobin Based Oxygen Carriers (HBOCs) on laboratory assays. The information presented for Hemopure ® also applies to Oxyglobin ®.
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Hemopure® has been used to treat surgical anemia in South Africa since 2001. Learn More
Oxyglobin® Solution
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